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When the Phagosome Gets Leaky: Pore-Forming Toxin-Induced Non-Canonical Autophagy (PINCA)

Macrophages remove bacteria from the extracellular milieu via phagocytosis. While most of the engulfed bacteria are degraded in the antimicrobial environment of the phagolysosome, several bacterial pathogens have evolved virulence factors, which evade degradation or allow escape into the cytosol. To...

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Detalles Bibliográficos
Autores principales: Herb, Marc, Gluschko, Alexander, Farid, Alina, Krönke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968195/
https://www.ncbi.nlm.nih.gov/pubmed/35372127
http://dx.doi.org/10.3389/fcimb.2022.834321