The Sphingolipid Inhibitors Ceranib-2 and SKI-II Reduce Measles Virus Replication in Primary Human Lymphocytes: Effects on mTORC1 Downstream Signaling

The bioactive sphingolipids ceramide and sphingosine-1-phosphate (S1P) are involved in the regulation of cell homeostasis and activity ranging from apoptosis to proliferation. We recently described that the two compounds ceranib-2 (inhibiting acid ceramidase) and SKI-II [inhibiting the sphingosine k...

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Detalles Bibliográficos
Autores principales: Chithelen, Janice, Franke, Hannah, Länder, Nora, Grafen, Anika, Schneider-Schaulies, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968423/
https://www.ncbi.nlm.nih.gov/pubmed/35370781
http://dx.doi.org/10.3389/fphys.2022.856143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968423/
https://www.ncbi.nlm.nih.gov/pubmed/35370781
http://dx.doi.org/10.3389/fphys.2022.856143

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