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Melatonin restores zinc levels, activates the Keap1/Nrf2 pathway, and modulates endoplasmic reticular stress and HSP in rats with chronic hepatotoxicity

BACKGROUND: Melatonin (MLT) is a potent antioxidant molecule that is shown to have a beneficial effect in various pathological situations, due to its action against free radicals. AIM: To evaluate the effect of MLT on carbon tetrachloride (CCl(4)) induced liver injury in rats in terms of oxidative s...

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Detalles Bibliográficos
Autores principales: Bona, Silvia, Fernandes, Sabrina Alves, Moreira, Andrea C Janz, Rodrigues, Graziella, Schemitt, Elizângela G, Di Naso, Fabio Cangeri, Marroni, Cláudio A, Marroni, Norma P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968507/
https://www.ncbi.nlm.nih.gov/pubmed/35433098
http://dx.doi.org/10.4292/wjgpt.v13.i2.11