Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis

BACKGROUND: The expression of amino acid transporters is known to vary during acute pancreatitis (AP) except for LAT1 (slc7a5), the expression of which remains stable. LAT1 supports cell growth by importing leucine and thereby stimulates mammalian target of rapamycin (mTOR) activity, a phenomenon of...

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Detalles Bibliográficos
Autores principales: Hagen, Cristina M, Roth, Eva, Graf, Theresia Reding, Verrey, François, Graf, Rolf, Gupta, Anurag, Pellegrini, Giovanni, Poncet, Nadège, Camargo, Simone Mafalda Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968515/
https://www.ncbi.nlm.nih.gov/pubmed/35431492
http://dx.doi.org/10.3748/wjg.v28.i10.1024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968515/
https://www.ncbi.nlm.nih.gov/pubmed/35431492
http://dx.doi.org/10.3748/wjg.v28.i10.1024

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