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Impact of Topical Interventions on the Vaginal Microbiota and Metabolome in Postmenopausal Women: A Secondary Analysis of a Randomized Clinical Trial

IMPORTANCE: Postmenopausal women with genitourinary symptoms of menopause are often prescribed vaginal estradiol or moisturizer for symptom improvement, but the impact of these treatments on the local microenvironment is poorly understood. OBJECTIVE: To compare changes in the vaginal microbiota, met...

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Detalles Bibliográficos
Autores principales: Srinivasan, Sujatha, Hua, Xing, Wu, Michael C., Proll, Sean, Valint, D. J., Reed, Susan D., Guthrie, Katherine A., LaCroix, Andrea Z., Larson, Joseph C., Pepin, Robert, Bhasin, Shalender, Raftery, Daniel, Fredricks, David N., Mitchell, Caroline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968546/
https://www.ncbi.nlm.nih.gov/pubmed/35353163
http://dx.doi.org/10.1001/jamanetworkopen.2022.5032