Cargando…

Impact of Topical Interventions on the Vaginal Microbiota and Metabolome in Postmenopausal Women: A Secondary Analysis of a Randomized Clinical Trial

IMPORTANCE: Postmenopausal women with genitourinary symptoms of menopause are often prescribed vaginal estradiol or moisturizer for symptom improvement, but the impact of these treatments on the local microenvironment is poorly understood. OBJECTIVE: To compare changes in the vaginal microbiota, met...

Descripción completa

Detalles Bibliográficos
Autores principales:	Srinivasan, Sujatha, Hua, Xing, Wu, Michael C., Proll, Sean, Valint, D. J., Reed, Susan D., Guthrie, Katherine A., LaCroix, Andrea Z., Larson, Joseph C., Pepin, Robert, Bhasin, Shalender, Raftery, Daniel, Fredricks, David N., Mitchell, Caroline M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968546/ https://www.ncbi.nlm.nih.gov/pubmed/35353163 http://dx.doi.org/10.1001/jamanetworkopen.2022.5032

Ejemplares similares

Association of Vaginal Estradiol Tablet With Serum Estrogen Levels in Women Who Are Postmenopausal: Secondary Analysis of a Randomized Clinical Trial
por: Mitchell, Caroline M., et al.
Publicado: (2022)

The Human Vaginal Bacterial Biota and Bacterial Vaginosis
por: Srinivasan, Sujatha, et al.
Publicado: (2008)

Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
por: Fredricks, David N, et al.
Publicado: (2020)

Complementing 16S rRNA Gene Amplicon Sequencing with Total Bacterial Load To Infer Absolute Species Concentrations in the Vaginal Microbiome
por: Tettamanti Boshier, Florencia A., et al.
Publicado: (2020)

Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome
por: Lee, Elliot M., et al.
Publicado: (2023)

Vaginal bacteria elicit acute inflammatory response in fallopian tube organoids: a model for pelvic inflammatory disease
por: Yu, Bo, et al.
Publicado: (2023)

Association between vaginal washing and vaginal bacterial concentrations
por: Sabo, Michelle C., et al.
Publicado: (2019)

Temporal Variability of Human Vaginal Bacteria and Relationship with Bacterial Vaginosis
por: Srinivasan, Sujatha, et al.
Publicado: (2010)

Genital Herpes Simplex Virus Type 2 Suppression With Valacyclovir Is Not Associated With Changes in Nugent Score or Absolute Abundance of Key Vaginal Bacteria
por: Babu, Tara M, et al.
Publicado: (2023)

THE WOMEN'S HEALTH INITIATIVE (WHI): STILL LEARNING FROM 161,808 POSTMENOPAUSAL WOMEN
por: LaCroix, Andrea Z, et al.
Publicado: (2019)

Changes in key vaginal bacteria among postpartum African women initiating intramuscular depot-medroxyprogesterone acetate
por: Whitney, Bridget M., et al.
Publicado: (2020)

Antiepileptic Drug Use, Falls, Fractures, and BMD in Postmenopausal Women: Findings From the Women's Health Initiative (WHI)
por: Carbone, Laura D, et al.
Publicado: (2010)

Postmenopausal Vaginal Microbiome and Microbiota
por: de Oliveira, Nayara Santos, et al.
Publicado: (2022)

Vaginal Flora in Postmenopausal Women: The Effect of Estrogen Replacement
por: Ginkel, Paul D., et al.
Publicado: (1993)

Metabolic Signatures of Bacterial Vaginosis
por: Srinivasan, Sujatha, et al.
Publicado: (2015)

More Than Meets the Eye: Associations of Vaginal Bacteria with Gram Stain Morphotypes Using Molecular Phylogenetic Analysis
por: Srinivasan, Sujatha, et al.
Publicado: (2013)

Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation
por: Noecker, Cecilia, et al.
Publicado: (2016)

Association of Physical Activity and Fracture Risk Among Postmenopausal Women
por: LaMonte, Michael J., et al.
Publicado: (2019)

Fertility Considerations in Adolescent Klinefelter Syndrome: Current Practice Patterns
por: Bhasin, Shalender, et al.
Publicado: (2019)

Associations Between Vaginal Bacteria and Bacterial Vaginosis Signs and Symptoms: A Comparative Study of Kenyan and American Women
por: Carter, Kayla A., et al.
Publicado: (2022)

Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study
por: Takacs, Peter, et al.
Publicado: (2019)

Current treatment options for postmenopausal vaginal atrophy
por: Naumova, Iuliia, et al.
Publicado: (2018)

Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women
por: Gliniewicz, Karol, et al.
Publicado: (2019)

Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria
por: Mitchell, Caroline M, et al.
Publicado: (2009)

Effect of Trigonella foenum (fenugreek) vaginal cream on vaginal atrophy in postmenopausal women
por: Mazalzadeh, Fakhriyeh, et al.
Publicado: (2020)

Obesity and risk of pancreatic cancer among postmenopausal women: the Women's Health Initiative (United States)
por: Luo, J, et al.
Publicado: (2008)

Cigarette smoking is associated with an altered vaginal tract metabolomic profile
por: Nelson, T. M., et al.
Publicado: (2018)

Cerebrospinal Fluid Metabolomics: Pilot Study of Using Metabolomics to Assess Diet and Metabolic Interventions in Alzheimer’s Disease and Mild Cognitive Impairment
por: Hanson, Angela J., et al.
Publicado: (2023)

An Unusual Case of Vaginal Myoma Presenting with Postmenopausal Bleeding
por: Goyal, Lajya Devi, et al.
Publicado: (2013)

The effect of vitamin D on vaginal atrophy in postmenopausal women
por: Rad, Parastou, et al.
Publicado: (2015)

Acceptability of the Dapivirine Vaginal Ring in Postmenopausal US Women
por: Shapley-Quinn, Mary Kate, et al.
Publicado: (2022)

Impact of preconception vaginal microbiota on women’s risk of spontaneous preterm birth: protocol for a prospective case-cohort study
por: Lokken, Erica M, et al.
Publicado: (2020)

Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial Vaginosis
por: Mitchell, Caroline, et al.
Publicado: (2009)

T4DM Trial and its T4Bone Substudy Shed Further Light on Effects of Testosterone Treatment in Middle-Aged and Older Men
por: Bhasin, Shalender, et al.
Publicado: (2021)

The effect of oxytocin vaginal gel on vaginal atrophy in postmenopausal women: a randomized controlled trial
por: Zohrabi, Ilnaz, et al.
Publicado: (2020)

Etiology of recurrent cystitis in postmenopausal women based on vaginal microbiota and the role of Lactobacillus vaginal suppository
por: Sekito, Takanori, et al.
Publicado: (2023)

Molecular analysis of the vaginal response to estrogens in the ovariectomized rat and postmenopausal woman
por: Jelinsky, Scott A, et al.
Publicado: (2008)

Leech Bite: A Rare Cause of Postmenopausal Vaginal Bleeding
por: Hasanzadeh Mofrad, M, et al.
Publicado: (2012)

Postmenopausal vaginal atrophy: evaluation of treatment with local estrogen therapy
por: Minkin, Mary Jane, et al.
Publicado: (2014)

Probiotics in the Prevention and Treatment of Postmenopausal Vaginal Infections: Review Article
por: Kim, Jun-Mo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f7hsfm1ehvtnfprkn8hituc7a1