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Characterization of Glycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary Myelofibrosis

Primary myelofibrosis (PMF) is a neoplasm prone to leukemic transformation, for which limited treatment is available. Among individuals diagnosed with PMF, the most prevalent mutation is the JAK2V617F somatic point mutation that activates the Janus kinase 2 (JAK2) enzyme. Our earlier reports on hype...

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Detalles Bibliográficos
Autores principales: Gaye, Maissa M., Ward, Christina M., Piasecki, Andrew J., Stahl, Vanessa L., Karagianni, Aikaterini, Costello, Catherine E., Ravid, Katya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968581/
https://www.ncbi.nlm.nih.gov/pubmed/35182768
http://dx.doi.org/10.1016/j.mcpro.2022.100213