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Genes Contributing to Resilience and Sensitivity to Lisinopril at Old Age: Clinical Translation of GWA in Drosophila

Despite impressive results in restoring physical performance in rodent models, treatment with Renin-Angiotensin System (RAS) inhibitors such as Lisinopril have highly mixed results in humans, likely, in part, due to genetic variation in human populations. To date, the genetic determinants of respons...

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Detalles Bibliográficos
Autores principales: Gabrawy, Mariann M, Khosravian, Nick, Morcos, George S, Jezek, Meagan, Walston, Jeremy, Abadir, Peter M, Leips, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968688/
http://dx.doi.org/10.1093/geroni/igab046.2555