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Genes Contributing to Resilience and Sensitivity to Lisinopril at Old Age: Clinical Translation of GWA in Drosophila
Despite impressive results in restoring physical performance in rodent models, treatment with Renin-Angiotensin System (RAS) inhibitors such as Lisinopril have highly mixed results in humans, likely, in part, due to genetic variation in human populations. To date, the genetic determinants of respons...
Autores principales: | Gabrawy, Mariann M, Khosravian, Nick, Morcos, George S, Jezek, Meagan, Walston, Jeremy, Abadir, Peter M, Leips, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968688/ http://dx.doi.org/10.1093/geroni/igab046.2555 |
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