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Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders: A Mendelian Randomization Study
IMPORTANCE: Previous in vitro and postmortem research suggests that inflammation may lead to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range of neuropsychiatric disorders. OBJECTIVE: To investigate the relationship between inflammation and changes in bra...
Autores principales: | Williams, John A., Burgess, Stephen, Suckling, John, Lalousis, Paris Alexandros, Batool, Fatima, Griffiths, Sian Lowri, Palmer, Edward, Karwath, Andreas, Barsky, Andrey, Gkoutos, Georgios V., Wood, Stephen, Barnes, Nicholas M., David, Anthony S., Donohoe, Gary, Neill, Joanna C., Deakin, Bill, Khandaker, Golam M., Upthegrove, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968718/ https://www.ncbi.nlm.nih.gov/pubmed/35353173 http://dx.doi.org/10.1001/jamapsychiatry.2022.0407 |
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