DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome

DIS3 gene mutations occur in roughly 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), which occur in approximately 40% of MM cases. Despite several reports on the prevalence of DIS3 mutations, their contribution to the pathobiology...

Descripción completa

Detalles Bibliográficos
Autores principales: Todoerti, Katia, Ronchetti, Domenica, Favasuli, Vanessa, Maura, Francesco, Morabito, Fortunato, Bolli, Niccolò, Taiana, Elisa, Neri, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968896/
https://www.ncbi.nlm.nih.gov/pubmed/33951891
http://dx.doi.org/10.3324/haematol.2021.278342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968896/
https://www.ncbi.nlm.nih.gov/pubmed/33951891
http://dx.doi.org/10.3324/haematol.2021.278342

Ejemplares similares