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DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome
DIS3 gene mutations occur in roughly 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), which occur in approximately 40% of MM cases. Despite several reports on the prevalence of DIS3 mutations, their contribution to the pathobiology...
Autores principales: | Todoerti, Katia, Ronchetti, Domenica, Favasuli, Vanessa, Maura, Francesco, Morabito, Fortunato, Bolli, Niccolò, Taiana, Elisa, Neri, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968896/ https://www.ncbi.nlm.nih.gov/pubmed/33951891 http://dx.doi.org/10.3324/haematol.2021.278342 |
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