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The complex karyotype landscape in chronic lymphocytic leukemia allows the refinement of the risk of Richter syndrome transformation

Complex karyotype (CK) at chronic lymphocytic leukemia (CLL) diagnosis is a negative biomarker of adverse outcome. Since the impact of CK and its subtypes, namely type-2 CK (CK with major structural abnormalities) or high-CK (CK with ≥5 chromosome abnormalities), on the risk of developing Richter sy...

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Detalles Bibliográficos
Autores principales: Visentin, Andrea, Bonaldi, Laura, Rigolin, Gian Matteo, Mauro, Francesca Romana, Martines, Annalisa, Frezzato, Federica, Pravato, Stefano, Gargarella, Leila Romano, Bardi, Maria Antonella, Cavallari, Maurizio, Volta, Eleonora, Cavazzini, Francesco, Nanni, Mauro, Facco, Monica, Piazza, Francesco, Guarini, Anna, Foà, Robin, Semenzato, Gianpietro, Cuneo, Antonio, Trentin, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968897/
https://www.ncbi.nlm.nih.gov/pubmed/34092056
http://dx.doi.org/10.3324/haematol.2021.278304