Cargando…
The mitochondrial anti-apoptotic dependencies of hematologic malignancies: from disease biology to advances in precision medicine
Mitochondria are critical organelles in the regulation of intrinsic apoptosis. As a general feature of blood cancers, different antiapoptotic members of the BCL-2 protein family localize at the outer mitochondrial membrane to sequester variable amounts of proapoptotic activators, and hence protect c...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Fondazione Ferrata Storti
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968907/ https://www.ncbi.nlm.nih.gov/pubmed/35045693 http://dx.doi.org/10.3324/haematol.2021.280201 |