Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis

CD64 (or FcγRIA) is the sole functional high affinity IgG Fc receptor coded by FCGR1A gene in humans. The FCGR1A genetics has not been comprehensively investigated and effects of human FCGR1A variants on immune functions remain unknown. In the current study, we identified three novel FCGR1A variants...

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Detalles Bibliográficos
Autores principales: Wu, Jianming, Li, Yunfang, Rendahl, Aaron, Bhargava, Maneesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968912/
https://www.ncbi.nlm.nih.gov/pubmed/35371020
http://dx.doi.org/10.3389/fimmu.2022.841099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968912/
https://www.ncbi.nlm.nih.gov/pubmed/35371020
http://dx.doi.org/10.3389/fimmu.2022.841099

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