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Acute Ketamine Facilitates Fear Memory Extinction in a Rat Model of PTSD Along With Restoring Glutamatergic Alterations and Dendritic Atrophy in the Prefrontal Cortex

Stress represents a major risk factor for psychiatric disorders, including post-traumatic stress disorder (PTSD). Recently, we dissected the destabilizing effects of acute stress on the excitatory glutamate system in the prefrontal cortex (PFC). Here, we assessed the effects of single subanesthetic...

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Detalles Bibliográficos
Autores principales: Sala, Nathalie, Paoli, Caterina, Bonifacino, Tiziana, Mingardi, Jessica, Schiavon, Emanuele, La Via, Luca, Milanese, Marco, Tornese, Paolo, Datusalia, Ashok K., Rosa, Jessica, Facchinetti, Roberta, Frumento, Giulia, Carini, Giulia, Salerno Scarzella, Floramarida, Scuderi, Caterina, Forti, Lia, Barbon, Alessandro, Bonanno, Giambattista, Popoli, Maurizio, Musazzi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968915/
https://www.ncbi.nlm.nih.gov/pubmed/35370690
http://dx.doi.org/10.3389/fphar.2022.759626