Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5′-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice

Neuroinflammation plays a key role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studies have shown that metformin exerts anti-inflammatory effects and promotes functional recovery in various central nervous system diseases. We designed this study to i...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Jin, Fa, Guo, Shenquan, Liu, Wenchao, Wei, Boyang, Fan, Haiyan, Li, Guangxu, Zhang, Xin, Su, Shixing, Li, Ran, Fang, Dazhao, Duan, Chuanzhi, Li, Xifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969021/
https://www.ncbi.nlm.nih.gov/pubmed/35370693
http://dx.doi.org/10.3389/fphar.2022.796616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969021/
https://www.ncbi.nlm.nih.gov/pubmed/35370693
http://dx.doi.org/10.3389/fphar.2022.796616

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