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In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial

BACKGROUND: The outcome of chemotherapy in patients older than 40 years with acute lymphoblastic leukaemia is poor and myeloablative allogeneic haematopoietic stem-cell transplantation (HSCT) has a high transplant-related mortality (TRM) in this age cohort. The aim of this study was to assess the ac...

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Detalles Bibliográficos
Autores principales: Marks, David I, Clifton-Hadley, Laura, Copland, Mhairi, Hussain, Jiaull, Menne, Tobias F, McMillan, Andrew, Moorman, Anthony V, Morley, Nicholas, Okasha, Dina, Patel, Bela, Patrick, Pip, Potter, Michael N, Rowntree, Clare J, Kirkwood, Amy A, Fielding, Adele K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969058/
https://www.ncbi.nlm.nih.gov/pubmed/35358442
http://dx.doi.org/10.1016/S2352-3026(22)00036-9