Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities

The constitutively active androgen receptor (AR) splice variant, AR-V7, plays an important role in resistance to androgen deprivation therapy in castration resistant prostate cancer (CRPC). Studies seeking to determine whether AR-V7 is a partial mimic of the AR, or also has unique activities, and wh...

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Detalles Bibliográficos
Autores principales: Basil, Paul, Robertson, Matthew J., Bingman, William E., Dash, Amit K., Krause, William C., Shafi, Ayesha A., Piyarathna, Badrajee, Coarfa, Cristian, Weigel, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969163/
https://www.ncbi.nlm.nih.gov/pubmed/35354884
http://dx.doi.org/10.1038/s41598-022-09371-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969163/
https://www.ncbi.nlm.nih.gov/pubmed/35354884
http://dx.doi.org/10.1038/s41598-022-09371-x

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