Gene knockdown of CCR3 reduces eosinophilic inflammation and the Th2 immune response by inhibiting the PI3K/AKT pathway in allergic rhinitis mice

The CCR3 gene plays a critical role in allergic airway inflammation, such as allergic rhinitis (AR), and there is an inflammatory signal link between the nasal cavity and the CCR3 gene in bone marrow. However, the effects of the CCR3 gene in bone marrow cells on AR are not clear. The present study i...

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Detalles Bibliográficos
Autores principales: Yuan, Jiasheng, Liu, Yuehui, Yu, Juan, Dai, Meina, Zhu, Yu, Bao, Youwei, Peng, Haisen, Liu, Ke, Zhu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969185/
https://www.ncbi.nlm.nih.gov/pubmed/35354939
http://dx.doi.org/10.1038/s41598-022-09467-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969185/
https://www.ncbi.nlm.nih.gov/pubmed/35354939
http://dx.doi.org/10.1038/s41598-022-09467-4

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