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Acetylation of Tau Induces Alzheimer's Disease-Associated Tau in Transgenic Mice

Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by neurofibrillary tangles (NFTs) and amyloid beta plaques. These NFTs are made up of aggregated tau proteins. Tau is involved in stabilizing microtubules and does not usually display aggregation. Acetylation of tau prote...

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Detalles Bibliográficos
Autores principales: Ali, Addison, Pareja, Kristeen, Tracy, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969302/
http://dx.doi.org/10.1093/geroni/igab046.3457