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Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing

BACKGROUND: Vascular invasion with tumor thrombus frequently occurs in advanced renal cell carcinoma (RCC). Thrombectomy is one of the most challenging surgeries with high rate of perioperative morbidity and mortality. However, the mechanisms driving tumor thrombus formation are poorly understood wh...

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Detalles Bibliográficos
Autores principales: Shi, Yue, Zhang, Qi, Bi, Hai, Lu, Min, Tan, Yezhen, Zou, Daojia, Ge, Liyuan, Chen, Zhigang, Liu, Cheng, Ci, Weimin, Ma, Lulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969307/
https://www.ncbi.nlm.nih.gov/pubmed/35361264
http://dx.doi.org/10.1186/s13059-022-02651-9