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APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

BACKGROUND: Apolipoprotein E epsilon 4 (APOE-ε4) carrier status is an established risk factor for Alzheimer’s disease (AD) dementia. It has also been linked with sleep disturbance in healthy older adults and increased insomnia risk. This association may be driven by the effect of APOE-ε4 on AD patho...

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Detalles Bibliográficos
Autores principales: Blackman, Jonathan, Love, Seth, Sinclair, Lindsey, Cain, Richard, Coulthard, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969347/
https://www.ncbi.nlm.nih.gov/pubmed/35354468
http://dx.doi.org/10.1186/s13195-022-00992-y