Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

BACKGROUND: Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oocyte mat...

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Detalles Bibliográficos
Autores principales: Yao, Zhongyuan, Zeng, Jun, Zhu, Huimin, Zhao, Jing, Wang, Xiaoxia, Xia, Qiuping, Li, Yanping, Wu, Lingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969352/
https://www.ncbi.nlm.nih.gov/pubmed/35354490
http://dx.doi.org/10.1186/s13048-022-00971-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969352/
https://www.ncbi.nlm.nih.gov/pubmed/35354490
http://dx.doi.org/10.1186/s13048-022-00971-9

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