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Impact of gene annotation choice on the quantification of RNA-seq data
BACKGROUND: RNA sequencing is currently the method of choice for genome-wide profiling of gene expression. A popular approach to quantify expression levels of genes from RNA-seq data is to map reads to a reference genome and then count mapped reads to each gene. Gene annotation data, which include c...
Autores principales: | Chisanga, David, Liao, Yang, Shi, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969366/ https://www.ncbi.nlm.nih.gov/pubmed/35354358 http://dx.doi.org/10.1186/s12859-022-04644-8 |
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