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CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind. Some of the major hurd...

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Detalles Bibliográficos
Autores principales: Pan, Kevin, Farrukh, Hizra, Chittepu, Veera Chandra Sekhar Reddy, Xu, Huihong, Pan, Chong-xian, Zhu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969382/
https://www.ncbi.nlm.nih.gov/pubmed/35361234
http://dx.doi.org/10.1186/s13046-022-02327-z