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Single molecule iSCAT imaging reveals a fast, energy efficient search mode for the DNA repair protein UvrA
Exposure to UV radiation results in numerous DNA lesions, which threaten genome integrity. The nucleotide excision DNA repair pathway detects and repairs a range of such UV-induced DNA lesions. In bacteria, initial damage detection and verification is carried out by two proteins: UvrA and UvrB. Desp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969456/ https://www.ncbi.nlm.nih.gov/pubmed/35311869 http://dx.doi.org/10.1039/d1nr06913f |