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Sevoflurane Induces Ferroptosis of Glioma Cells Through Activating the ATF4-CHAC1 Pathway

OBJECTIVE: To clarify the function and mechanisms of sevoflurane (Sev) on ferroptosis in glioma cells. METHODS: Different concentrations of Sev were used to treat glioma cells U87 and U251. Ferroptosis inducer Erastin was used to incubate glioma cells combined with Sev and ATF4 siRNA transfection tr...

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Detalles Bibliográficos
Autores principales: Xu, Yingyi, Zhang, Na, Chen, Cheng, Xu, Xinke, Luo, Ailing, Yan, Yaping, Lu, Yanhua, Liu, Jianhua, Ou, Xinxu, Tan, Yonghong, Liang, Yufeng, Chen, Lihe, Song, Xingrong, Liu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969566/
https://www.ncbi.nlm.nih.gov/pubmed/35372041
http://dx.doi.org/10.3389/fonc.2022.859621