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Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis

Chitinase 1 (CHIT1) and chitinase 3-like-1 (CHI3L1), two representative members of 18-Glycosyl hydrolases family, are significantly implicated in the pathogenesis of various human diseases characterized by inflammation and remodeling. Notably, dysregulated expression of CHIT1 and CHI3L1 was noted in...

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Detalles Bibliográficos
Autores principales: Lee, Suh-Young, Lee, Chang-Min, Ma, Bing, Kamle, Suchitra, Elias, Jack A., Zhou, Yang, Lee, Chun Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969576/
https://www.ncbi.nlm.nih.gov/pubmed/35370755
http://dx.doi.org/10.3389/fphar.2022.826471