MxB Disrupts Hepatitis C Virus NS5A–CypA Complex: Insights From a Combined Theoretical and Experimental Approach

The human myxovirus resistance B (MxB) protein is an interferon-induced restriction factor that fights a wide range of viruses. We previously demonstrated that MxB binds to hepatitis C virus (HCV)-encoded non-structural protein 5A (NS5A) and inhibits HCV infection by impairing the formation of cyclo...

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Detalles Bibliográficos
Autores principales: Li, Quanjie, An, Ni, Yin, Xiao, Zhang, Ruixin, Shao, Huihan, Yi, Dongrong, Cen, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969595/
https://www.ncbi.nlm.nih.gov/pubmed/35369502
http://dx.doi.org/10.3389/fmicb.2022.849084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969595/
https://www.ncbi.nlm.nih.gov/pubmed/35369502
http://dx.doi.org/10.3389/fmicb.2022.849084

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