A Single Amino Acid Substitution in Structural Protein VP2 Abrogates the Neurotropism of Enterovirus A-71 in Mice

Enterovirus 71 (EV-A71) causes hand, foot, and mouth disease (HFMD) in children and has been associated with neurological complications. With no specific treatment and a monovalent vaccine limited to the Chinese market, HFMD remains a serious public health concern and an economic burden to affected...

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Detalles Bibliográficos
Autores principales: Yeo, Huimin, Chong, Connie Wan Hui, Chen, Elijah Weihua, Lim, Ze Qin, Ng, Qing Yong, Yan, Benedict, Chu, Justin Jang Hann, Chow, Vincent T. K., Alonso, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969769/
https://www.ncbi.nlm.nih.gov/pubmed/35369482
http://dx.doi.org/10.3389/fmicb.2022.821976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969769/
https://www.ncbi.nlm.nih.gov/pubmed/35369482
http://dx.doi.org/10.3389/fmicb.2022.821976

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