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Determining the Effects of Neddylation on Cullin‐RING Ligase–Dependent Protein Ubiquitination
As the largest family of ubiquitin (Ub) E3 ligases, cullin‐RING ligases (CRLs) play crucial roles in various cellular processes, and their activities are tightly regulated by orchestrated mechanisms. Neddylation, the conjugation of a Ub‐like protein NEDD8 to a target protein such as the cullin, repr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8969890/ https://www.ncbi.nlm.nih.gov/pubmed/35316580 http://dx.doi.org/10.1002/cpz1.401 |