Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer

ONC201 is a promising first-in-class small molecule that has been reported to have anti-neoplastic activity in various types of cancer through activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as well as activation of mitochondrial caseinolytic protease P (ClpP). The pres...

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Bibliographic Details
Main Authors: Fan, Yali, Wang, Jiandong, Fang, Ziwei, Pierce, Stuart R., West, Lindsay, Staley, Allison, Tucker, Katherine, Yin, Yajie, Sun, Wenchuan, Kong, Weimin, Prabhu, Varun, Allen, Joshua E., Zhou, Chunxiao, Bae-Jump, Victoria L.
Format: Online Article Text
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
Oncology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970020/
https://www.ncbi.nlm.nih.gov/pubmed/35372029
http://dx.doi.org/10.3389/fonc.2022.789450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970020/
https://www.ncbi.nlm.nih.gov/pubmed/35372029
http://dx.doi.org/10.3389/fonc.2022.789450

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