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Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer
ONC201 is a promising first-in-class small molecule that has been reported to have anti-neoplastic activity in various types of cancer through activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as well as activation of mitochondrial caseinolytic protease P (ClpP). The pres...
Hauptverfasser: | , , , , , , , , , , , , , |
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Format: | Online Artikel Text |
Sprache: | English |
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Frontiers Media S.A.
2022
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Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970020/ https://www.ncbi.nlm.nih.gov/pubmed/35372029 http://dx.doi.org/10.3389/fonc.2022.789450 |