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SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is accompanied by chronic neurological sequelae such as cognitive decline and mood disorder, but the underlying mechanisms have not yet been elucidated. We explored the possibility that the brain-infiltrating SARS-CoV-2 spike pro...

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Detalles Bibliográficos
Autores principales: Oh, Junyoung, Cho, Woo-Hyun, Barcelon, Ellane, Kim, Kwang Hwan, Hong, Jinpyo, Lee, Sung Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970073/
https://www.ncbi.nlm.nih.gov/pubmed/35361832
http://dx.doi.org/10.1038/s41598-022-09410-7