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Amyloid fibril composition type is consistent over time in patients with Val30Met (p.Val50Met) transthyretin amyloidosis

BACKGROUND: We have previously shown that transthyretin (TTR) amyloidosis patients have amyloid fibrils of either of two compositions; type A fibrils consisting of large amounts of C-terminal TTR fragments in addition to full-length TTR, or type B fibrils consisting of only full-length TTR. Since ty...

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Detalles Bibliográficos
Autores principales: Anan, Intissar, Suhr, Ole B., Liszewska, Katarzyna, Mejia Baranda, Jorge, Pilebro, Björn, Wixner, Jonas, Ihse, Elisabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970372/
https://www.ncbi.nlm.nih.gov/pubmed/35358243
http://dx.doi.org/10.1371/journal.pone.0266092