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The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro

Intracellular transport via microtubule-based dynein and kinesin family motors plays a key role in viral reproduction and transmission. We show here that Kinesin Family Member 4 (KIF4) plays an important role in HBV/HDV infection. We intended to explore host factors impacting the HBV life cycle that...

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Detalles Bibliográficos
Autores principales: Gad, Sameh A., Sugiyama, Masaya, Tsuge, Masataka, Wakae, Kosho, Fukano, Kento, Oshima, Mizuki, Sureau, Camille, Watanabe, Noriyuki, Kato, Takanobu, Murayama, Asako, Li, Yingfang, Shoji, Ikuo, Shimotohno, Kunitada, Chayama, Kazuaki, Muramatsu, Masamichi, Wakita, Takaji, Nozaki, Tomoyoshi, Aly, Hussein H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970526/
https://www.ncbi.nlm.nih.gov/pubmed/35312737
http://dx.doi.org/10.1371/journal.ppat.1009983