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Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Generation of oligodendrocytes in the adult brain enables both adaptive changes in neural circuits and regeneration of myelin sheaths destroyed by injury, disease, and normal aging. This transformation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes requires processing of...

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Detalles Bibliográficos
Autores principales: Heo, Dongeun, Ling, Jonathan P, Molina-Castro, Gian C, Langseth, Abraham J, Waisman, Ari, Nave, Klaus-Armin, Möbius, Wiebke, Wong, Phil C, Bergles, Dwight E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970587/
https://www.ncbi.nlm.nih.gov/pubmed/35311646
http://dx.doi.org/10.7554/eLife.75230