Dedicated chaperones coordinate co-translational regulation of ribosomal protein production with ribosome assembly to preserve proteostasis

The biogenesis of eukaryotic ribosomes involves the ordered assembly of around 80 ribosomal proteins. Supplying equimolar amounts of assembly-competent ribosomal proteins is complicated by their aggregation propensity and the spatial separation of their location of synthesis and pre-ribosome incorpo...

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Detalles Bibliográficos
Autores principales: Pillet, Benjamin, Méndez-Godoy, Alfonso, Murat, Guillaume, Favre, Sébastien, Stumpe, Michael, Falquet, Laurent, Kressler, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970588/
https://www.ncbi.nlm.nih.gov/pubmed/35357307
http://dx.doi.org/10.7554/eLife.74255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970588/
https://www.ncbi.nlm.nih.gov/pubmed/35357307
http://dx.doi.org/10.7554/eLife.74255

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