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High-resolution mapping demonstrates inhibition of DNA excision repair by transcription factors

DNA base damage arises frequently in living cells and needs to be removed by base excision repair (BER) to prevent mutagenesis and genome instability. Both the formation and repair of base damage occur in chromatin and are conceivably affected by DNA-binding proteins such as transcription factors (T...

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Detalles Bibliográficos
Autores principales: Duan, Mingrui, Sivapragasam, Smitha, Antony, Jacob S, Ulibarri, Jenna, Hinz, John M, Poon, Gregory MK, Wyrick, John J, Mao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970589/
https://www.ncbi.nlm.nih.gov/pubmed/35289750
http://dx.doi.org/10.7554/eLife.73943