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An acid trip activates protumoral macrophages to promote hepatocellular carcinoma malignancy

Tumor-associated macrophages (TAMs) promote metastasis and tumor cell extravasation, survival, and growth. In hepatocellular carcinoma (HCC), the presence of TAM subpopulations correlates with poor outcome. In this issue of the JCI, Ning et al. report on their use of cell culture, mouse models, and...

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Detalles Bibliográficos
Autores principales: Graham, Nicola, Pollard, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970664/
https://www.ncbi.nlm.nih.gov/pubmed/35362482
http://dx.doi.org/10.1172/JCI158562