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Carbonic anhydrase XII mediates the survival and prometastatic functions of macrophages in human hepatocellular carcinoma

Macrophages constitute a major immune component in tumor tissues, but how these cells adapt to and survive in the nutrient-depleted and lactic acid–induced acidic tumor microenvironments is not yet fully understood. Here, we found that levels of carbonic anhydrase XII (CA12) expression were signific...

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Detalles Bibliográficos
Autores principales: Ning, Wan-Ru, Jiang, Da, Liu, Xing-Chen, Huang, Yu-Fan, Peng, Zhi-Peng, Jiang, Ze-Zhou, Kang, Tiebang, Zhuang, Shi-Mei, Wu, Yan, Zheng, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970669/
https://www.ncbi.nlm.nih.gov/pubmed/35362480
http://dx.doi.org/10.1172/JCI153110