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Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway

Kidney is one of the most vulnerable organs in sepsis, resulting in sepsis-associated acute kidney injury (SA-AKI), which brings about not only morbidity but also mortality of sepsis. Ferroptosis is a new kind of death type of cells elicited by iron-dependent lipid peroxidation, which participates i...

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Detalles Bibliográficos
Autores principales: Qiongyue, Zhang, Xin, Yang, Meng, Peng, Sulin, Mi, Yanlin, Wang, Xinyi, Li, Xuemin, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970707/
https://www.ncbi.nlm.nih.gov/pubmed/35370723
http://dx.doi.org/10.3389/fphar.2022.857067