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Tetramethylpyrazine Improves Monocrotaline-Induced Pulmonary Hypertension through the ROS/iNOS/PKG-1 Axis

BACKGROUND: Tetramethylpyrazine (TMP), a potent anti-free radical and anti-inflammations substance, has been demonstrated to possess a direct vessel relaxation property. This study aimed to evaluate the effect of TMP treatment in pulmonary hypertension (PH) and test the hypothesis that TMP prevents...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Peng, Dong, Wen-Peng, Yang, Yong-Chao, Zeng, Yuan-Yuan, Liu, Ying, Dong, Zhu, Ma, Xi-Miao, Cao, Yi-Qiu, Bai, Yi-Zhou, Yang, Bo, Wang, Xiao-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970814/
https://www.ncbi.nlm.nih.gov/pubmed/35368928
http://dx.doi.org/10.1155/2022/1890892