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Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy

Chemotherapy has been used to inhibit cancer growth for decades, but emerging evidence shows it can affect the tumor stroma, unintentionally promoting cancer malignancy. After treatment of primary tumors, remaining drugs drain via lymphatics. Though all drugs interact with the lymphatics, we know li...

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Detalles Bibliográficos
Autores principales: Harris, Alexandra R., Esparza, Savieay, Azimi, Mohammad S., Cornelison, Robert, Azar, Francesca N., Llaneza, Danielle C., Belanger, Maura, Mathew, Alexander, Tkachenko, Svyatoslav, Perez, Matthew J., Rosean, Claire Buchta, Bostic, Raegan R., Cornelison, R. Chase, Tate, Kinsley M., Peirce-Cottler, Shayn M., Paquette, Cherie, Mills, Anne, Landen, Charles N., Saucerman, Jeff, Dillon, Patrick M., Pompano, Rebecca R., Rutkowski, Melanie A., Munson, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8970967/
https://www.ncbi.nlm.nih.gov/pubmed/35372032
http://dx.doi.org/10.3389/fonc.2022.801764