PD-L1 blockade exhibits anti-tumor effect on brain metastasis by activating CD8(+) T cells in hematogenous metastasis model with lymphocyte infusion

Brain metastases are common complication in cancer patients. Immune checkpoint inhibitors show therapeutic benefits also in patients with central nervous system (CNS) metastases. However, their antitumor effects on metastatic tumors and their underlying mechanisms are still poorly understood. In thi...

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Detalles Bibliográficos
Autores principales: Masuda, Chinami, Morinaga, Mamiko, Wakita, Daiko, Yorozu, Keigo, Kurasawa, Mitsue, Sugimoto, Masamichi, Kondoh, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971192/
https://www.ncbi.nlm.nih.gov/pubmed/34797455
http://dx.doi.org/10.1007/s10585-021-10135-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971192/
https://www.ncbi.nlm.nih.gov/pubmed/34797455
http://dx.doi.org/10.1007/s10585-021-10135-6

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