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RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway

Chemotherapy is the first-line treatment for human retinoblastoma (RB), but the occurrence of drug resistance greatly limited its efficacy in practice. RING-finger protein 6 (RNF6) is an E3 ubiquitin ligase that is aberrantly upregulated in a range of cancers and plays important roles in cancer prog...

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Detalles Bibliográficos
Autores principales: Chai, Yong, Jiao, Shoufeng, Peng, Xin, Gan, Qiang, Chen, Leifeng, Hu, Xiaolu, Hao, Liang, Zhang, Shouhua, Tao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971205/
https://www.ncbi.nlm.nih.gov/pubmed/35369571
http://dx.doi.org/10.3389/pore.2022.1610273