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Taking Lessons from CAR-T Cells and Going Beyond: Tailoring Design and Signaling for CAR-NK Cells in Cancer Therapy

Cancer immunotherapies utilize the capabilities of the immune system to efficiently target malignant cells. In recent years, chimeric antigen receptor (CAR) equipped T cells showed promising results against B cell lymphomas. Autologous CAR-T cells require patient-specific manufacturing and thus exte...

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Detalles Bibliográficos
Autores principales: Ruppel, Katharina Eva, Fricke, Stephan, Köhl, Ulrike, Schmiedel, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971283/
https://www.ncbi.nlm.nih.gov/pubmed/35371071
http://dx.doi.org/10.3389/fimmu.2022.822298