A repositioning screen using an FGFR2 splicing reporter reveals compounds that regulate epithelial-mesenchymal transitions and inhibit growth of prostate cancer xenografts

Research in the area of hallmarks of cancer has opened the possibility of designing new therapies based on modulating these cancer properties. We present here a screen designed to find chemicals that modulate epithelial-mesenchymal transitions (EMTs) in prostate cancer. For screening, we used a repu...

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Detalles Bibliográficos
Autores principales: Li, Ling, Zheng, Jinxia, Stevens, Megan, Oltean, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971352/
https://www.ncbi.nlm.nih.gov/pubmed/35402635
http://dx.doi.org/10.1016/j.omtm.2022.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971352/
https://www.ncbi.nlm.nih.gov/pubmed/35402635
http://dx.doi.org/10.1016/j.omtm.2022.03.005

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