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Associations with response to Poly(ADP-ribose) Polymerase (PARP) inhibitors in patients with metastatic breast cancer

PARP inhibitors (PARPi) have modest antitumor activity in patients with advanced breast cancer and mutation in BRCA. It is unclear whether some subgroups derive greater benefit from treatment. MEDLINE and EMBASE were searched from inception to March 2021 to identify trials of PARPi in patients with...

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Detalles Bibliográficos
Autores principales: Desnoyers, A., Nadler, M., Wilson, B. E., Stajer, S., Amir, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971397/
https://www.ncbi.nlm.nih.gov/pubmed/35361769
http://dx.doi.org/10.1038/s41523-022-00405-1